abstract：:Myogenic differentiation 1 (MyoD1) genes belong to the MyoD gene family and play key roles in growth and muscle development. This study was designed to investigate the effects of variants in the MyoD1 gene on duck growth and carcass traits. Three duck populations (Cherry Valley, Jingjiang, and Muscovy) were sampled, t...

journal_title：Biochemical genetics

authors： Wu Y,Pi JS,Pan AL,Pu YJ,Du JP,Shen J,Liang ZH,Zhang JR

更新日期：2012-12-01 00:00:00

abstract：:The goals of this study were to analyze the change in the global gene expression profile of exogenous human leukocyte antigen-G1 (HLA-G1) overexpressed in human embryonic stem (hES) cells and to explore the molecular mechanism by which the overexpression of HLA-G1 modifies immunologic pathways. Microarray and quantita...

journal_title：Biochemical genetics

authors： Zhu Y,Zhao S,Zhao H,Yao Y

更新日期：2012-10-01 00:00:00

abstract：:Single-chain variable fragment (scFv) is one of the most common antibody forms. This report describes the expression of the scFv gene as a soluble protein in Origami DE3 cytoplasm. The purified scFv recognized the epidermal growth factor receptor (EGFRvIII) on the surface of MCF-7 cells. The scFv protein was purified ...

journal_title：Biochemical genetics

authors： Mahgoub IO

更新日期：2012-08-01 00:00:00

abstract：:In this study, we identified porcine single nucleotide polymorphisms (SNPs) by aligning eight sequences generated with two approaches: amplification of 665 intronic regions using one sample from each of eight breeds, including three East Asian pigs, and amplification of 289 3'-UTR regions using two samples from each o...

journal_title：Biochemical genetics

authors： Matsumoto T,Okumura N,Uenishi H,Hayashi T,Hamasima N,Awata T

更新日期：2012-06-01 00:00:00

abstract：:Seasonal changes in genetic diversity of Meriones meridianus and Dipus sagitta populations in the Ningxia Hui Autonomous Region were monitored using inter-simple sequence repeats. There were 45 discernible DNA fragments isolated from 33 samples of M. meridianus, and 25 from 40 samples of D. sagitta. The differences in...

journal_title：Biochemical genetics

authors： Zhou R,Li Y,Li JQ,Liu NF

更新日期：2012-06-01 00:00:00

abstract：:Human PQBP-1 is known to interact with triplet repeat disease gene products such as ataxin and huntingtin through their poly-glutamine (poly-Q) tracts. The poly-Q tracts show extensive variation in both the number and the configuration of repeats among species. A surface plasmon resonance assay showed clear interactio...

journal_title：Biochemical genetics

authors： Kurosaki T,Gojobori J,Ueda S

更新日期：2012-04-01 00:00:00

abstract：:The nuclear factor of activated T lymphocytes (NFATc1) plays a critical role during valvular and septal development. Genetic variants may influence the biological function of the protein and thus play a role in susceptibility to valvuloseptal defects. Tandem repeat polymorphisms and a common nonsynonymous polymorphism...

journal_title：Biochemical genetics

authors： Gu H,Gong J,Qiu W,Cao H,Xu J,Chen S,Chen Y

更新日期：2011-10-01 00:00:00

abstract：:To determine the genetic structure and variation of Van cats and some other cats, seven enzyme loci were examined using horizontal starch gel electrophoresis. ME bands were observed for the first time in cats. For the enzyme loci CA ( 1 ), SOD, GPI, and GOT, neither the individual Van cats nor the specimens of other c...

journal_title：Biochemical genetics

authors： Altunok V,Yüksek N,Berkman CC,Ağaoğlu ZT,Togan I

更新日期：2011-08-01 00:00:00

abstract：:The allele, genotype, and haplotype frequencies among 837 Polish Holstein-Friesian cattle were determined at two regulatory indel polymorphisms of the PRNP gene. Allele frequencies at the 23 bp indel promoter polymorphism were 0.622 (del) and 0.378 (ins), with 0.613 and 0.387 in sires and 0.633 and 0.366 in dams. Alle...

journal_title：Biochemical genetics

authors： Czarnik U,Strychalski J,Zabolewicz T,Pareek CS

更新日期：2011-06-01 00:00:00

abstract：:A major category of mutant hematopoietic phenotypes in Drosophila is melanotic tumors or nodules, which consist of abnormal and overproliferated blood cells, similar to granulomas. Our analyses of the melanotic mutant dappled have revealed a novel type of gene involved in blood cell regulation. The dappled gene is an ...

journal_title：Biochemical genetics

authors： Kleinhesselink K,Conway C,Sholer D,Huang I,Kimbrell DA

更新日期：2011-06-01 00:00:00

abstract：:The retinal pigment epithelium (RPE) plays a key role in the maintenance of the normal functions of the retina. Tissue engineering using amniotic membrane as a substrate to culture RPE cells may provide a promising new strategy to replace damaged RPE. We established a method of culturing RPE cells over the amniotic me...

journal_title：Biochemical genetics

authors： Akrami H,Soheili ZS,Sadeghizadeh M,Khalooghi K,Ahmadieh H,Kanavi MR,Samiei S,Pakravesh J

更新日期：2011-06-01 00:00:00

abstract：:This haplotype-based case-control study investigated whether the aldosterone synthase gene (CYP11B2) might be implicated in the pathogenesis of essential hypertension in Yi (226 individuals) and Hani (296 individuals) minorities of China. Four tag SNPs (rs4536, rs4545, rs3097, and rs3802230) and the K173R polymorphism...

journal_title：Biochemical genetics

authors： Chen B,Nie S,Yue Z,Shou W,Xiao C

更新日期：2011-02-01 00:00:00

abstract：:Site-specific gene modifications in cells are initiated by the introduction of exogenous DNA. We used a recently established cell assay to compare the ability of DNA donors to induce a single point mutation that converts a target gene encoding blue fluorescent protein (BFP) into expressing green fluorescent protein (G...

journal_title：Biochemical genetics

authors： Wagner S,McCracken J,Cole S,Laible G

更新日期：2010-12-01 00:00:00

abstract：:Aggrecan is the major component of intervertebral disk matrix proteoglycan with multiple functional domains. To understand the role of aggrecan polymorphism in a part of exon 12 encoding the CS1 domain in lumbar disk degeneration disease, we have analyzed genomic DNA from 71 patients with the disease and 108 healthy i...

journal_title：Biochemical genetics

authors： Mashayekhi F,Shafiee G,Kazemi M,Dolati P

更新日期：2010-08-01 00:00:00

abstract：:Studies on hybridization, inheritance, and population genetics of brown planthoppers that infest rice and weeds were undertaken using starch gel electrophoresis to determine whether the weed-infesting population represents a biological race or a species. F(1) and F(2) generations were produced by crosses between paren...

journal_title：Biochemical genetics

authors： Latif MA,Omar MY,Tan SG,Siraj SS,Ismail AR

更新日期：2010-04-01 00:00:00

abstract：:Nucleophosmin/nucleoplasmin has been studied mostly in mammals and amphibians. To clarify the characteristics and function of nucleophosmin/nucleoplasmin in teleost fish, we cloned a full-length cDNA sequence from two cyprinid fish, Carassius auratus gibelio and Carassius auratus. Molecular characterization and multip...

journal_title：Biochemical genetics

authors： Wu N,Li CJ,Gui JF

更新日期：2009-12-01 00:00:00

abstract：:The variable numbers of tandem repeats (VNTR) locus D1S80, located on chromosome 1 (1p35-36), has a repeat unit 16 bp in length, and different numbers of these repeat units have been observed for populations of different origins and ethnicity. We used a molecular identification method based on capillary electrophoresi...

journal_title：Biochemical genetics

authors： Köseler A,Atalay A,Atalay EO

更新日期：2009-08-01 00:00:00

abstract：:Fifty-six sequences encoding the pina protein were characterized from three species or subspecies of einkorn wheat. These sequences contained 1,595 nucleotides, including 1,270 conserved sites, 21 single nucleotide polymorphisms (SNPs), and 16 indels. The average frequency of SNPs and indels was one out of 76.1 and 99...

journal_title：Biochemical genetics

authors： Chen Q,Qi PF,Wei YM,Wang JR,Zheng YL

更新日期：2009-06-01 00:00:00

abstract：:The cryptic plasmid pGY1, which is harbored by a clinical isolate of Salmonella enterica serovar Paratyphi A, was identified in a 9-year-old girl with paratyphoid fever in 2005, and its DNA sequence was determined. It is 3592 bp in length and had a G+C content of 43.3%. Three ORFs were predicted that share low similar...

journal_title：Biochemical genetics

authors： Huang H,Li J,Yang XL,Wang YG,Wang YP,Tao JS,Huang YZ,Zhang XL

更新日期：2009-04-01 00:00:00

abstract：:Nicotiana rustica L. HZNH, a native Chinese tobacco germplasm, displays a hypersensitive response (HR) and systemic acquired resistance following infection with tobacco mosaic virus (TMV). A resistance gene, CN, cloned from HZNH plants, was homologous to the N and NH genes identified in other Nicotiana species. The CN...

journal_title：Biochemical genetics

authors： Zhang GY,Chen M,Guo JM,Xu TW,Li LC,Xu ZS,Ma YZ,Chen XP

更新日期：2009-04-01 00:00:00

abstract：:The taxonomy of the genus Hypostomus in the upper Rio Paraná basin presents some very complex issues. For this reason, an allozyme electrophoresis survey of 10 populations of Hypostomus from the Rio Corumbá basin was performed, revealing 25 loci from 14 enzyme systems. Allozyme data revealed diagnostic genetic markers...

journal_title：Biochemical genetics

authors： Zawadzki CH,Renesto E,Mateus RP

更新日期：2008-12-01 00:00:00

abstract：:A plausible approach to evaluate the inhibitory action of antifungals is through the investigation of the fungal resistance to these drugs. We describe here the molecular cloning and initial characterization of the A. nidulans lipA gene, where mutation (lipA1) conferred resistance to undecanoic acid, the most fungitox...

journal_title：Biochemical genetics

authors： Brito-Madurro AG,Prade RA,Madurro JM,Santos MA,Peres NT,Cursino-Santos JR,Martinez-Rossi NM,Rossi A

更新日期：2008-10-01 00:00:00

abstract：:The genetic diversity of the Turkish native chicken breeds Denizli and Gerze was evaluated with 10 microsatellite markers. We genotyped a total of 125 individuals from five subpopulations. Among loci, the mean number of alleles was 7.5, expected heterozygosity (H (e)) was 0.665, PIC value was 0.610, and Wright's fixat...

journal_title：Biochemical genetics

authors： Kaya M,Yildiz MA

更新日期：2008-08-01 00:00:00

abstract：:The solute carrier family 11 member 1 (SLC11A1) protein plays important roles in macrophage activation and displays pleiotropic effects on various macrophage functions, including the regulation of tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), and oxidative burst. Considering the important role...

journal_title：Biochemical genetics

authors： Kim EJ,Kim KM,Park SH,Kim JS,Lee WK,Cha SI,Kim CH,Kang YM,Han SB,Jung TH,Park JY

更新日期：2008-08-01 00:00:00

abstract：:This work examines the molecular evolution of a brain-expressed X-linked gene family in the mammalian genomes of human, chimp, macaque, mouse, rat, dog, and cow. The gene structures are well conserved across family members and among the mammals in that all five members have three exons with the first two exons untrans...

journal_title：Biochemical genetics

authors： Zhang L

更新日期：2008-06-01 00:00:00

abstract：:The secretogranin II (SCG2) gene is associated with the synthesis and secretion of follicle-stimulating hormone and luteinizing hormone. In the present study, we have determined the complete cDNA sequence of pig SCG2, which was submitted to GenBank with accession no. AY870646. Its complete open reading frame of 1,851 ...

journal_title：Biochemical genetics

authors： Du HL,Chen J,Zhang YS,Zhang XQ

更新日期：2008-06-01 00:00:00

abstract：:Polymorphism of the mtDNA ND5 gene was detected by PCR-SSCP and DNA sequencing methods in 714 individuals from six Chinese cattle breeds. The results showed that at the P2 locus, two kinds of haplotypes, named A and B, with three SNPs (T12900C, A12923T, C12924T) were detected. The frequencies of haplotype A in six bre...

journal_title：Biochemical genetics

authors： Zhang B,Chen H,Hua L,Zhang C,Kang X,Wang X,Pan C,Lan X,Lei C

更新日期：2008-06-01 00:00:00

abstract：:Ubiquitin-specific protease 9, Y-linked (USP9Y), is a protein encoded by the Y chromosome. Its precise function in the cell is unknown, although a role in the regulation of protein turnover has been postulated. Nonetheless, mutations in this gene could result in the over- or under-abundance of proteins involved in the...

journal_title：Biochemical genetics

authors： Sims LM,Ballantyne J

更新日期：2008-04-01 00:00:00

abstract：:Genetic diversity and genetic structure within and among ten populations of Stephania yunnanensis H. S. Lo and three populations of S. epigaea H. S. Lo from Yunnan province were evaluated by direct amplification of length polymorphism (DALP) markers. Five primer groups were screened, and a total of 287 DNA fragments w...

journal_title：Biochemical genetics

authors： Ma YS,Yu H,Li YY,Yan H,Cheng X

更新日期：2008-04-01 00:00:00

abstract：:Markhors (Capra falconeri) are among the most endangered mammal species, and several conservation measures, including ex situ breeding, are implemented to prevent their extinction. We studied sequence diversity and differentiation of the first hypervariable segment of the mitochondrial DNA control region among C. f. h...

journal_title：Biochemical genetics

authors： Hammer SE,Schwammer HM,Suchentrunk F

更新日期：2008-04-01 00:00:00

abstract：:The stem-loop potential of a nucleic acid segment (expressed as a FONS value), decomposes into base composition-dependent and base order-dependent components. The latter, expressed as a FORS-D value, is derived by subtracting the value of the base composition-dependent component (FORS-M) from the FONS value. FORS-D an...

journal_title：Biochemical genetics

authors： Zhang CY,Wei JF,Wu JS,Xu WR,Sun X,He SH

更新日期：2008-02-01 00:00:00

abstract：:The East Himalaya-Hengduan Mountains region is the center of diversity of the genus Primula, and P. sikkimensis is one of the most common members of the genus in the region. In this study, the genetic diversity and structure of P. sikkimensis populations in China were assessed using inter-simple sequence repeat (ISSR)...

journal_title：Biochemical genetics

authors： Wang FY,Ge XJ,Gong X,Hu CM,Hao G

更新日期：2008-02-01 00:00:00

abstract：:In this study, the geographic patterns of genetic variation of three rodent species belonging to the tribe Oryzomyini were investigated using the mitochondrial cytochrome b and nuclear IRBP genes in biomes that are undergoing degradation processes to a greater or lesser degree. The samples are from 25 collecting local...

journal_title：Biochemical genetics

authors： Miranda GB,Andrades-Miranda J,Oliveira LF,Langguth A,Mattevi MS

更新日期：2007-12-01 00:00:00

abstract：:The single-strand conformation polymorphism (SSCP) procedure has been applied in routine testing for hereditary diseases. Temperature, running buffer, gel composition, and fragment length can influence its sensitivity. Mutation detection in the clinical setting depends on the development of automated technology, espec...

journal_title：Biochemical genetics

authors： Okamoto Y,Ueta A,Sumi S,Ito T,Okubo Y,Jose Y,Ninomiya A,Togari H,Nishida M

更新日期：2007-10-01 00:00:00

abstract：:Information on genetic variation is essential for conservation and stock improvement programs. Seven dinucleotide microsatellite loci were analyzed to reveal genetic variability in three wild populations (Kella beel, Hakaluki haor, and Shobornokhali beel) and one hatchery population of the freshwater walking catfish, ...

journal_title：Biochemical genetics

authors： Islam MN,Islam MS,Alam MS

更新日期：2007-10-01 00:00:00

abstract：:Among the European fauna, the Sardinian hare (Lepus sp.) is peculiar in that it differs from all other hares inhabiting the continent. Here, we report on the variation of a 461 bp sequence of hypervariable domain 1 of the mitochondrial control region, examined in 42 hares collected throughout Sardinia and compared to ...

journal_title：Biochemical genetics

authors： Scandura M,Iacolina L,Ben Slimen H,Suchentrunk F,Apollonio M

更新日期：2007-04-01 00:00:00

abstract：:Genetic variation and differentiation of 12 populations of Picea jezoensis from the Russian Far East were studied using 20 allozyme loci. The mean number of alleles per locus was 2.63, the percent of polymorphic loci was 88.1%, the observed heterozygosity was 0.181, and the mean value of expected heterozygosity amount...

journal_title：Biochemical genetics

authors： Potenko VV

更新日期：2007-04-01 00:00:00

abstract：:Species in the genus Oryza (Poaceae) contain 10 genomic types and are distributed in pan-tropics of the world. To explore phylogenetic relationships of Oryza species having the AA-genome, DNA sequences of the chloroplast trnL intron and trnL-trnF spacer, mitochondrial nad1 intron 2, and nuclear internal transcribed sp...

journal_title：Biochemical genetics

authors： Duan S,Lu B,Li Z,Tong J,Kong J,Yao W,Li S,Zhu Y

更新日期：2007-02-01 00:00:00

abstract：:Random amplified polymorphic DNA was used to assess the level of genetic diversity and genetic structure of Stipa krylovii (Gramineae), an important dominant species in the northern grasslands of China. Genetic diversity was low within S. krylovii populations, and diversity at the population level was associated with ...

journal_title：Biochemical genetics

authors： Zhao NX,Gao YB,Wang JL,Ren AZ

更新日期：2006-12-01 00:00:00

abstract：:Luo [Biochem. Genet. 43:223-227] concluded, "The mutation ALDH2(() 487Lys allele is not deleterious but is of great benefit to human health." This statement is easily subject to misinterpretation and needs to be clarified. Their results actually show there is a pleiotropic effect associated with the mutation ALDH2(() ...

journal_title：Biochemical genetics

authors： Sinclair D

更新日期：2006-10-01 00:00:00